This model simulates sleep in the human brain and is consistent with both the flip/flop concept and the two-process model of sleep regulation. The model also gives a possible mechanism for the changes in sleep timing seen in narcolepsy.
Model Type: Realistic Network
Transmitters: Gaba
Model Concept(s): Sleep
Simulation Environment: XPPAUT
Implementer(s): Rempe, Michael [mrempe at whitworth.edu]
References:
Rempe MJ, Best J, Terman D. (2010). A mathematical model of the sleep/wake cycle. Journal of mathematical biology 60 [PubMed]