A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)


The model uses realistically coupled, discretised, Wilson-Cowan units to describe the spatio-temporal activity of a cortical sheet. This model has been used the investigate the dynamic onset mechanisms of focal seizures.

Model Type: Neural mass

Model Concept(s): Oscillations; Spatio-temporal Activity Patterns; Epilepsy; Delay; Brain Rhythms; Bifurcation

Simulation Environment: MATLAB

Implementer(s): Wang, Yujiang [yujiang.wang at newcastle.ac.uk]

References:

Wang Y, Goodfellow M, Taylor PN, Baier G. (2014). Dynamic mechanisms of neocortical focal seizure onset. PLoS computational biology. 10 [PubMed]


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