Microglial cytokine network (Anderson et al., 2015)

This is an ODE model of autocrine/paracrine microglial cytokine interactions. Simulations include analyses of neuroinflammation mechanisms in the context of adaptation and tolerance to LPS.

Model Type: Glia; Molecular Network

Cell Type(s): Microglia; Macrophage

Model Concept(s): Cytokine Signaling

Simulation Environment: MATLAB; MATLAB (web link to model)

Implementer(s): Anderson, Warren D [warren.anderson at jefferson.edu]

References:

Anderson WD et al. (2015). Computational modeling of cytokine signaling in microglia. Molecular bioSystems. 11 [PubMed]