"This portal provides an online public resource of the Blue Brain Project's first release of a digital reconstruction of the microcircuitry of juvenile Rat somatosensory cortex, access to experimental data sets used in the reconstruction, and the resulting models."
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse
Region(s) or Organism(s): Barrel cortex
Model Concept(s): Spatio-temporal Activity Patterns; Detailed Neuronal Models
Simulation Environment: NEURON (web link to model); NeuroML (web link to model)
References:
Markram H et al. (2015). Reconstruction and Simulation of Neocortical Microcircuitry. Cell 163 [PubMed]
Ramaswamy S et al. (2015). The neocortical microcircuit collaboration portal: a resource for rat somatosensory cortex. Frontiers in neural circuits 9 [PubMed]
Reimann MW, King JG, Muller EB, Ramaswamy S, Markram H. (2015). An algorithm to predict the connectome of neural microcircuits. Frontiers in computational neuroscience 9 [PubMed]
Abdellah M et al. (2017). Reconstruction and visualization of large-scale volumetric models of neocortical circuits for physically-plausible in silico optical studies. BMC bioinformatics 18 [PubMed]
Reimann MW et al. (2017). Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function. Frontiers in computational neuroscience 11 [PubMed]
Gal E et al. (2017). Rich cell-type-specific network topology in neocortical microcircuitry. Nature neuroscience 20 [PubMed]
Reimann MW, Horlemann AL, Ramaswamy S, Muller EB, Markram H. (2017). Morphological Diversity Strongly Constrains Synaptic Connectivity and Plasticity. Cerebral cortex (New York, N.Y. : 1991) 27 [PubMed]
Barros-Zulaica N et al. (2019). Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex Frontiers in Synaptic Neuroscience 11