Spikelet generation and AP initiation in a simplified pyr neuron (Michalikova et al. 2017) Fig 3


The article by Michalikova et al. (2017) explores the generation of spikelets in cortical pyramidal neurons. This package contains code for simulating the model with simplified morphology shown in Figs 3 and S2.

Model Type: Neuron or other electrically excitable cell; Axon

Currents: I Na,t

Model Concept(s): Action Potentials; Electrotonus; Action Potential Initiation; Axonal Action Potentials

Simulation Environment: NEURON; Python

Implementer(s): Michalikova, Martina [tinka.michalikova at gmail.com]

References:

Michalikova M, Remme MW, Kempter R. (2017). Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma. PLoS computational biology 13 [PubMed]