Network model of a hippocampal circuit including interneurons and principal cells. Amplitude and decay time course of inhibitory synapses can be systematically changed for different distances between connected cells. Various forms of excitatory drives can be administered to the network including spatially structured input.
Model Type: Realistic Network
Region(s) or Organism(s): Dentate gyrus
Cell Type(s): Dentate gyrus granule GLU cell; Dentate gyrus basket cell
Model Concept(s): Gamma oscillations; Spatio-temporal Activity Patterns
Simulation Environment: NEURON
Implementer(s): Strüber, Michael [michael_strueber at hotmail.com]
Strüber M, Sauer JF, Jonas P, Bartos M. (2017). Distance-dependent inhibition facilitates focality of gamma oscillations in the dentate gyrus. Nature communications 8 [PubMed]