" ... Here, we established experimentally and theoretically that contributions of axons to EFPs can be significant. Modeling action potentials propagating along axons, we showed that EFPs were prominent in the presence of terminal zones where axons branch and terminate in close succession, as found in many brain regions. Our models predicted a dipolar far field and a polarity reversal at the center of the terminal zone. ..."
Model Type: Axon; Extracellular
Region(s) or Organism(s): Brainstem; Auditory brainstem
Cell Type(s): Nucleus laminaris neuron
Model Concept(s): Action Potentials
Simulation Environment: NEURON (web link to model); Python (web link to model)
Implementer(s): McColgan, Thomas
References:
McColgan T et al. (2017). Dipolar extracellular potentials generated by axonal projections. eLife. 6 [PubMed]