Olfactory Mitral Cell (Davison et al 2000)


A four-compartment model of a mammalian olfactory bulb mitral cell, reduced from the complex 286-compartment model described by Bhalla and Bower (1993). The compartments are soma/axon, secondary dendrites, primary dendrite shaft and primary dendrite tuft. The reduced model runs 75 or more times faster than the full model, making its use in large, realistic network models of the olfactory bulb practical.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Olfactory bulb main mitral GLU cell

Currents: I Na,t; I L high threshold; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium; I Potassium

Model Concept(s): Parameter Fitting; Simplified Models; Olfaction

Simulation Environment: NEURON

Implementer(s): Davison, Andrew [Andrew.Davison at iaf.cnrs-gif.fr]

References:

Davison AP, Feng J, Brown D. (2000). A reduced compartmental model of the mitral cell for use in network models of the olfactory bulb. Brain research bulletin. 51 [PubMed]


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