This models are used to evaluate which factors influence the GDP (giant depolarizing potential) induced [Cl-]I transients based on a initial model of P. Jedlicka
Model Type: Neuron or other electrically excitable cell; Dendrite; Synapse
Region(s) or Organism(s): Mouse; Hippocampus
Cell Type(s): Hippocampus CA3 pyramidal GLU cell
Receptors: GabaA
Transmitters: Gaba
Model Concept(s): Synaptic Plasticity
Simulation Environment: NEURON
References:
Lombardi A, Jedlicka P, Luhmann HJ, Kilb W. (2019). Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration International journal of molecular sciences. 20 [PubMed]