The ventricular AP and effects of the isoproterenol-induced cardiac hypertrophy (Sengul et al 2020)

This model reproduces Action Potential (AP) of Rat Ventricular Myocytes according to the experimental AP and Voltage Clamp recordings.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Mouse

Cell Type(s): Cardiac ventricular cell

Currents: I Sodium; I_Ks; I Cl, leak; I Na, leak; I K,leak; I_Na,Ca; Na/K pump; Ca pump

Model Concept(s): Action Potentials

Simulation Environment: MATLAB

Implementer(s): Sircan, Ahmet Kürsad [ahmetkursadsircan at gmail.com]

References:

Şengül Ayan S et al. (2020). Mathematical model of the ventricular action potential and effects of the isoproterenol-induced cardiac hypertrophy in rats European biophysics journal : EBJ. 49 [PubMed]