Leech Heart Interneuron model (Sharma et al 2020)


Fractional order Leech heart interneuron model is investigated. Different firing properties are explored. In this article, we investigate the alternation of spiking and bursting phenomena of an uncoupled and coupled fractional Leech-Heart (L-H) neurons. We show that a complete graph of heterogeneous de-synchronized neurons in the backdrop of diverse memory settings (a mixture of integer and fractional exponents) can eventually lead to bursting with the formation of cluster synchronization over a certain threshold of coupling strength, however, the uncoupled L-H neurons cannot reveal bursting dynamics. Using the stability analysis in fractional domain, we demarcate the parameter space where the quiescent or steady-state emerges in uncoupled L-H neuron. Finally, a reduced-order model is introduced to capture the activities of the large network of fractional-order model neurons.

Model Type: Realistic Network

Region(s) or Organism(s): Leech

Cell Type(s): Leech heart interneuron

Model Concept(s): Oscillations; Bifurcation

Simulation Environment: MATLAB

References:

Sharma SK, Mondal A, Mondal A, Upadhyay RK, Hens C. (2020). Emergence of bursting in a network of memory dependent excitable and spiking leech-heart neurons. Journal of the Royal Society, Interface. 17 [PubMed]


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