"A MATLAB-based model of pyramidal-interneuron network was extended from [modeldb.yale.edu/138421]... to simulate how intrinsic biophysical properties and inhibition can affect network synchrony and oscillatory frequencies in ACC L3 and L5... Four different networks were simulated depending on a subset of empirically derived biophysical, morphological and connectional properties of lamina- and target- specific ACC pyramidal neurons... our model is constrained by in vitro whole cell patch clamp recording data from the soma."
Cell Type(s): Hodgkin-Huxley neuron; Abstract Wang-Buzsaki neuron
Model Concept(s): Oscillations; Action Potentials; Spike Frequency Adaptation
Simulation Environment: MATLAB
References:
Chang W et al. (2021). Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks Cerebral Cortex.