This version of the Integrated Oscillator Model has two PFK isoforms, as well as modules for oxidative phosphorylation, electrical activity, and intracellular calcium.
Model Type: Neuron or other electrically excitable cell
Currents: ATP-senstive potassium current
Model Concept(s): Bursting
Simulation Environment: XPPAUT
Implementer(s): Bertram, Richard [rbertram at fsu.edu]
References:
Marinelli I et al. (2022). Slow Oscillations Persist in Pancreatic Beta Cells Lacking Phosphofructokinase M Biophysical journal 121 [PubMed]