Spinal Motor Neuron (Dodge, Cooley 1973)

"The excitability of various regions of the spinal motorneuron can be specified by solving the partial differential equation of a nerve fiber whose diameter and membrane properties vary with distance. For our model geometrical factors for the myelinated axon, initial segment and cell body were derived from anatomical measurements, the dendritic tree was represented by its equivalent cylinder, and the current-voltage relations of the membrane were described by a modification of the Hodgkin-Huxley model that fits voltage-clamp data from the motorneuron. ..."

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell; Myelinated neuron

Currents: I Na,t; I K

Model Concept(s): Simplified Models; Active Dendrites; Tutorial/Teaching; Axonal Action Potentials; Action Potentials

Simulation Environment: NEURON

Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]

References:

Cooley JW, Dodge FA. (1973). Action Potential of the Motorneuron. IBM J Res Dev. 17