We present a model for a conditional bursting neuron consisting of five conductances: Hodgkin-Huxley type time- and voltage-dependent Na+ and K+ conductances, a calcium activated voltage-dependent K+ conductance, a calcium-inhibited time- and voltage-dependent Ca++ conductance, and a leakage Cl- conductance. Different bursting and silent modes and transitions between them are analyzed in the model and compared to bursting modes in experiment. See the paper for details.
Model Type: Neuron or other electrically excitable cell
Currents: I Chloride; I Na,t; I K; I Sodium; I Calcium; I Potassium
Model Concept(s): Bursting; Invertebrate
Simulation Environment: SNNAP
Implementer(s): Baxter, Douglas
References:
Epstein IR, Marder E. (1990). Multiple modes of a conditional neural oscillator. Biological cybernetics. 63 [PubMed]