A model of the transient, low-threshold voltage-dependent (T-type) Ca2+ current is constructed using whole-cell voltage-clamp data from enzymatically isolated rat thalamocortical relay neurons. The T-type Ca2+ current is described according to the Hodgkin-Huxley scheme, using the m3h format, with rate constants determined from the experimental data.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell
Currents: I T low threshold
Model Concept(s): Activity Patterns; Ion Channel Kinetics; Oscillations
Simulation Environment: NEURON
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu]
References:
Wang XJ, Rinzel J, Rogawski MA. (1991). A model of the T-type calcium current and the low-threshold spike in thalamic neurons. Journal of neurophysiology. 66 [PubMed]