In this paper, we present a method by which the activation and kinetic properties of INa, IK can be estimated from current-clamp data, more precisely from the time course of the action potential, provided some additional electrophysiological properties of the neurone are a priori known. See reference for details and more.
Model Type: Channel/Receptor
Model Concept(s): Ion Channel Kinetics; Methods
Simulation Environment: Octave
Implementer(s): Toth, T.I [toth at cardiff.ac.uk]
References:
Tóth TI, Crunelli V. (2001). Estimation of the activation and kinetic properties of I(Na) and I(K) from the time course of the action potential. Journal of neuroscience methods. 111 [PubMed]