Nav1.6 sodium channel model in globus pallidus neurons (Mercer et al. 2007)


Model files for the paper Mercer JN, Chan CS, Tkatch T, Held J, Surmeier DJ. Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons.,J Neurosci. 2007 Dec 5;27(49):13552-66.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Globus pallidus neuron

Currents: I Na,p; I Na,t; I K; I h; I K,Ca; I Sodium; I Calcium; I Potassium

Genes: Nav1.6 SCN8A

Model Concept(s): Action Potential Initiation; Action Potentials; Parkinson's

Simulation Environment: NEURON

Implementer(s): Held, Joshua [j-held at northwestern.edu]

References:

Mercer JN, Chan CS, Tkatch T, Held J, Surmeier DJ. (2007). Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]


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