"In Parkinson’s disease, neurons of the internal segment of the globus pallidus (GPi) display the low-frequency tremor-related oscillations. These oscillatory activities are transmitted to the thalamic relay nuclei. Computer models of the interacting thalamocortical (TC) and thalamic reticular (RE) neurons were used to explore how the TC-RE network processes the low-frequency oscillations of the GPi neurons. ..."
Region(s) or Organism(s): Thalamus
Model Concept(s): Parkinson's
Simulation Environment: MATLAB
Implementer(s): Hadipour-Niktarash, Arash [arash.hadipour at gmail.com]
Hadipour-Niktarash A. (2006). A computational model of how an interaction between the thalamocortical and thalamic reticular neurons transforms the low-frequency oscillations of the globus pallidus. Journal of computational neuroscience. 20 [PubMed]