High frequency oscillations induced in three gap-junction coupled neurons (Tseng et al. 2008)

Here we showed experimentally that high frequency oscillations (up to 600 Hz) were easily induced in a purely gap-junction coupled network by simple two stimuli with very short interval. The root cause is that the second elicited spike suffered from slow propagation speed and failure to transmit through a low-conductance junction. Similiar results were also obtained in these simulation.

Model Type: Axon

Cell Type(s): Hodgkin-Huxley neuron

Model Concept(s): Action Potential Initiation; Axonal Action Potentials; Action Potentials; Delay; Conduction failure

Simulation Environment: NEURON

Implementer(s): Tseng, Shin-Hua


Tseng SH, Tsai LY, Yeh SR. (2008). Induction of high-frequency oscillations in a junction-coupled network. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

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