Gap junction coupled network of striatal fast spiking interneurons (Hjorth et al. 2009)

Gap junctions between striatal FS neurons has very weak ability to synchronise spiking. Input uncorrelated between neighbouring neurons is shunted, while correlated input is not.

Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite

Region(s) or Organism(s): Basal ganglia

Cell Type(s): Neostriatum fast spiking interneuron

Currents: I A; I_K,Na

Transmitters: Gaba; Glutamate

Model Concept(s): Activity Patterns; Ion Channel Kinetics; Synchronization; Detailed Neuronal Models

Simulation Environment: GENESIS; MATLAB

Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se]

References:

Hjorth J, Blackwell KT, Kotaleski JH. (2009). Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]