Electrically-coupled Retzius neurons (Vazquez et al. 2009)

"Dendritic electrical coupling increases the number of effective synaptic inputs onto neurons by allowing the direct spread of synaptic potentials from one neuron to another. Here we studied the summation of excitatory postsynaptic potentials (EPSPs) produced locally and arriving from the coupled neuron (transjunctional) in pairs of electrically-coupled Retzius neurons of the leech. We combined paired recordings of EPSPs, the production of artificial EPSPs (APSPs) in neuron pairs with different coupling coefficients and simulations of EPSPs produced in the coupled dendrites. ..."

Model Type: Realistic Network; Neuron or other electrically excitable cell

Region(s) or Organism(s): Leech

Cell Type(s): Leech Retzius neuron

Currents: I Na,t; I A; I K; I K,Ca; I Calcium

Model Concept(s): Synaptic Integration

Simulation Environment: NEURON


Vazquez Y, Mendez B, Trueta C, De-Miguel FF. (2009). Summation of excitatory postsynaptic potentials in electrically-coupled neurones. Neuroscience. 163 [PubMed]

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