"Chaotic regimes in a mathematical model of pacemaker activity in the bursting neurons of a snail Helix pomatia, have been investigated. The model includes a slow-wave generating mechanism, a spike-generating mechanism, an inward Ca current, intracellular Ca ions, [Ca2+]in, their fast buffering and uptake by intracellular Ca stores, and a [Ca2+]in-inhibited Ca current. Chemosensitive voltage-activated conductance, gB*, responsible for termination of the spike burst, and chemosensitive sodium conductance, gNa*, responsible for the depolarization phase of the slow-wave, were used as control parameters. ... Time courses of the membrane potential and [Ca2+]in were employed to analyse different regimes in the model. ..."
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Helix pomatia (snail)
Cell Type(s): Helix pacemaker bursting neuron (RPa1)
Currents: I Na,t; I K; I Calcium
Model Concept(s): Activity Patterns; Bursting; Invertebrate; Calcium dynamics
Simulation Environment: XPPAUT
Implementer(s): Komendantov, Alexander O [akomenda at tulane.edu]
References:
Komendantov AO, Kononenko NI. (1996). Deterministic chaos in mathematical model of pacemaker activity in bursting neurons of snail, Helix pomatia. Journal of theoretical biology. 183 [PubMed]