Temporal sensitivity of signaling pathways underlying L-LTP. Single compartment, deterministic model of calcium and dopamine activated pathways, leading to CaMKII and PKA activation. Experimental verification of model prediction.
Model Type: Synapse
Cell Type(s): Hippocampus CA1 pyramidal GLU cell
Receptors: Dopaminergic Receptor
Simulation Environment: XPPAUT
Implementer(s): Blackwell, Avrama [avrama at gmu.edu]