Calcium waves in neuroblastoma cells (Fink et al. 2000)

Uses a model of IP3-mediated release of Ca from endoplasmic reticulum (ER) to study how initiation and propagation of Ca waves are affected by cell geometry, spatial distributions of ER and IP3 generation, and diffusion of Ca and mobile buffer.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Unknown

Cell Type(s): Neuroblastoma

Currents: I_SERCA

Receptors: IP3

Model Concept(s): Calcium dynamics; Calcium waves

Simulation Environment: NEURON; Virtual Cell (web link to model)

Implementer(s): Carnevale, Ted [Ted.Carnevale at]; Fink, Charles C [cfink at]


Fink CC et al. (2000). An image-based model of calcium waves in differentiated neuroblastoma cells. Biophysical journal. 79 [PubMed]

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