"... A minimal mathematical model was developed for a preliminary study of long-range neural transmission of gamma oscillation from the CA3 to the entorhinal cortex via the CAI region of the hippocampus, a subset within a larger complex set of pathways. A module was created for each local population of neurons with common intrinsic properties and connectivity to simplify the connection process and make the model more flexible. Three modules were created using MATLAB Simulink® and tested to confirm that they transmit gamma through the system. The model also revealed that a portion of the signal from CAI to the entorhinal cortex may be lost in transmission under certain conditions."
Model Type: Realistic Network
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA3 pyramidal GLU cell
Model Concept(s): Oscillations; Simplified Models
Simulation Environment: MATLAB
Implementer(s): Murray, Teresa A. [bioengineer1 at hotmail.com]
References:
Murray TA. (2007). Model of long-range transmission of gamma oscillation Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering Kohala Coast Hawaii. SaD1.29