Laminar analysis of excitatory circuits in vibrissal motor and sensory cortex (Hooks et al. 2011)


"... We mapped local excitatory pathways in each area (primary motor cortex (vM1), primary somatosensory cortex (vS1; barrel cortex), and secondary somatosensory cortex (S2)) across all cortical layers using glutamate uncaging and laser scanning photostimulation. We analyzed these maps to derive laminar connectivity matrices describing the average strengths of pathways between individual neurons in different layers and between entire cortical layers. ..."

Model Type: Realistic Network

Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell

Model Concept(s): Activity Patterns; Connectivity matrix; Laminar Connectivity; Touch; Whisking

Simulation Environment: MATLAB

References:

Hooks BM et al. (2011). Laminar analysis of excitatory local circuits in vibrissal motor and sensory cortical areas. PLoS biology. 9 [PubMed]


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