Three models of increasing complexity all showing a switch from type II (biphasic) to type I (monophasic) phase response curves with a cholinergic down-modulation of K+ conductances.
Cell Type(s): Neocortex L2/3 pyramidal GLU cell
Model Concept(s): Action Potentials
Simulation Environment: NEURON
Implementer(s): Stiefel, Klaus [stiefel at salk.edu]
Stiefel KM, Gutkin BS, Sejnowski TJ. (2009). The effects of cholinergic neuromodulation on neuronal phase-response curves of modeled cortical neurons. Journal of computational neuroscience. 26 [PubMed]