"... The primary objective of this modeling study was to determine the effects of axonal conduction velocity (often neglected, but significant), as well as synaptic time constants, on the ability of such a network to create and propagate cortical waves. ... The model is also being used to study the interaction between single and two-tone input and normal background activity, and the effects of synaptic depression from thalamic inputs. The simulation scripts have the additional purpose of serving as tutorial examples for the construction of cortical networks with GENESIS. The present model has fostered the development of the G-3 Python network analysis and visualization tools used in this study... It is my hope that this short tutorial and the example simulation scripts can provide a head start for a graduate student or postdoc who is beginning a cortical modeling project. "
Model Type: Realistic Network
Region(s) or Organism(s): Auditory cortex
Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Neocortex V1 interneuron basket PV GABA cell
Model Concept(s): Activity Patterns; Tutorial/Teaching
Simulation Environment: GENESIS
Implementer(s): Beeman, Dave
References:
Beeman D. (2013). A modeling study of cortical waves in primary auditory cortex BMC Neuroscience. 14(Supl 1)