"... Here we demonstrate that biophysical models of channel noise can give rise to two kinds of recently discovered stochastic facilitation effects in a Hodgkin-Huxley-like model of auditory brainstem neurons. The first, known as slope-based stochastic resonance (SBSR), enables phasic neurons to emit action potentials that can encode the slope of inputs that vary slowly relative to key time constants in the model. The second, known as inverse stochastic resonance (ISR), occurs in tonically firing neurons when small levels of noise inhibit tonic firing and replace it with burstlike dynamics. ... our results show that possible associated computational benefits may occur due to channel noise in neurons of the auditory brainstem. ... "
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Stomatogastric ganglion (STG) pyloric dilator (PD) neuron; Stomatogastric ganglion (STG) pyloric neuron
Currents: I A; I K,leak; I h; I K,Ca; I Sodium; I Calcium
Model Concept(s): Bursting; Parameter sensitivity; Temperature; Audition
Simulation Environment: C or C++ program
Implementer(s): Caplan, Jonathan S [joncaplan at gmail.com]
Caplan JS, Williams AH, Marder E. (2014). Many parameter sets in a multicompartment model oscillator are robust to temperature perturbations. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]