This study investigates the mechanisms that are affected in the striatal network after dopamine depletion and identifies potential therapeutic targets to restore normal activity.
Simulation Environment: GENESIS
Implementer(s): Damodaran, Sriraman [dsriraman at gmail.com]
Damodaran S, Cressman JR, Jedrzejewski-Szmek Z, Blackwell KT. (2015). Desynchronization of fast-spiking interneurons reduces ß-band oscillations and imbalance in firing in the dopamine-depleted striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35 [PubMed]