" ... In this paper, to reproduce ISO (Infra-Slow Oscillations) in neural networks, we show that dopaminergic modulation of STDP is essential. More specifically, we discovered a close relationship between two dopaminergic effects: modulation of the STDP function and generation of ISO. We therefore, numerically investigated the relationship in detail and proposed a possible mechanism by which ISO is generated."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Abstract Izhikevich neuron
Receptors: D1; D5; Dopaminergic Receptor
Transmitters: Dopamine
Model Concept(s): STDP; Synaptic Plasticity; Long-term Synaptic Plasticity; Oscillations
Simulation Environment: C or C++ program
References:
Kobayashi T, Shimada Y, Fujiwara K, Ikeguchi T. (2017). Reproducing Infra-Slow Oscillations with Dopaminergic Modulation. Scientific reports. 7 [PubMed]