Dendritic spine geometry, spine apparatus organization: spatiotemporal Ca dynamics (Bell et al 2019)

" ... we systematically investigated the relationship between the shape and size of both the spine head and spine apparatus, a specialized endoplasmic reticulum compartment within the spine head, in modulating rapid calcium dynamics using mathematical modeling. ..."

Model Type: Synapse

Currents: I Calcium; I K

Receptors: NMDA

Model Concept(s): Reaction-diffusion; Calcium dynamics; Signaling pathways

Simulation Environment: COMSOL (web link to model)

Implementer(s): Bell, Miriam


Bell M, Bartol T, Sejnowski T, Rangamani P. (2019). Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium. The Journal of general physiology. 151 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.