Here we used a 10,000 neuron model. The neurons are a mixture of excitatory and inhibitory integrate-and-fire neurons connected with synapses that exhibit synaptic depression. Three different connectivity paradigms were tested to look for spontaneous transition between interictal spiking and seizure: uniform, small-world network, and scale-free. All three model types are included here.
Model Type: Connectionist Network
Cell Type(s): Abstract integrate-and-fire neuron
Simulation Environment: C or C++ program
Implementer(s): Jacob, Theju
Jacob T et al. (2019). A Proposed Mechanism for Spontaneous Transitions between Interictal and Ictal Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 39 [PubMed]