Model for pancreatic beta-cells (Law et al. 2020)

This model is used to explain how chronic stimulation of pancreatic beta-cells can lead to compensation that restores calcium oscillations and electrical bursting.

Model Type: Neuron or other electrically excitable cell

Currents: I K; I Calcium; I K,Ca

Model Concept(s): Bursting; Calcium dynamics

Simulation Environment: XPPAUT


Law NC et al. (2020). Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro. American journal of physiology. Endocrinology and metabolism. 318 [PubMed]

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