"... Here, we show that Locus Coeruleus (LC) cells projecting to dCA1 have a key permissive role in contextual memory linking, without affecting contextual memory formation, and that this effect is mediated by dopamine. Additionally, we found that LC to dCA1 projecting neurons modulate the excitability of dCA1 neurons, and the extent of overlap between dCA1 memory ensembles, as well as the stability of coactivity patterns within these ensembles..."
Region(s) or Organism(s): Hippocampus
Cell Type(s): Abstract integrate-and-fire neuron
Implementer(s): Kastellakis, George [gkastel at gmail.com]