A single compartment model of Drosophila motor neuron (Megwa et al 2023)


This is a single compartment model aparted from Drosophilia larval crawl motor neuron data as described in Megwa, Pascual, Gunay, Pulver, Prinz (2023). The model contains Fast and Slow Potassium currents, Transient and Persistent Sodium Currents, Sodium and Potassium Leak Currents, and a NA/K Pump. No Calcium and Potassium concentrations aren't tracked.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Drosophila

Cell Type(s): Hodgkin-Huxley neuron; Abstract single compartment conductance based cell

Currents: Na/K pump; I K; I K,leak; I Na, leak; I Na,t; I Na,p; I_Ks; I Sodium

Model Concept(s): Action Potentials; Electrical-chemical; Memory; Membrane Properties; Simplified Models; Sodium pump; Bursting; Information transfer; Activity Patterns; Invertebrate

Simulation Environment: Python

Implementer(s): Prinz, Astrid [astrid.prinz at emory.edu]; Gunay, Cengiz [cgunay at emory.edu]; Megwa, Obinna [omegwa@emory.edu]

References:


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