Aplysia LTF model (Liu et al, 2020; Zhang et al, 2021; Liu et al 2022)

Model Type: Molecular Network

Cell Type(s): Aplysia sensory neuron

Transmitters: Serotonin

Model Concept(s): Memory

Simulation Environment: XPPAUT

References:

Liu RY, Zhang Y, Smolen P, Cleary LJ, Byrne JH. (2020). Role of p90 ribosomal S6 kinase in long-term synaptic facilitation and enhanced neuronal excitability Scientific reports. 10 [PubMed]

Zhang Y, Smolen PD, Cleary LJ, Byrne JH. (2021). Quantitative description of the interactions among kinase cascades underlying long-term plasticity of Aplysia sensory neurons Scientific reports. 11 [PubMed]

Liu RY, Zhang Y, Smolen P, Cleary LJ, Byrne JH. (2022). Defective synaptic plasticity in a model of Coffin-Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways Learning & memory (Cold Spring Harbor, N.Y.). 29 [PubMed]