Arthur JS et al. (2004). Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]
Bartsch D, Casadio A, Karl KA, Serodio P, Kandel ER. (1998). CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell. 95 [PubMed]
Bartsch D et al. (1995). Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell. 83 [PubMed]
Cleary LJ, Lee WL, Byrne JH. (1998). Cellular correlates of long-term sensitization in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]
Han JH et al. (2007). Neuronal competition and selection during memory formation. Science (New York, N.Y.). 316 [PubMed]
Liu RY, Cleary LJ, Byrne JH. (2011). The requirement for enhanced CREB1 expression in consolidation of long-term synaptic facilitation and long-term excitability in sensory neurons of Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]
Liu RY, Fioravante D, Shah S, Byrne JH. (2008). cAMP response element-binding protein 1 feedback loop is necessary for consolidation of long-term synaptic facilitation in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]
Liu RY et al. (2013). Deficit in long-term synaptic plasticity is rescued by a computationally predicted stimulus protocol. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]
Lonze BE, Ginty DD. (2002). Function and regulation of CREB family transcription factors in the nervous system. Neuron. 35 [PubMed]
Martin KC et al. (1997). MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron. 18 [PubMed]
Montarolo PG et al. (1986). A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science (New York, N.Y.). 234 [PubMed]
Mozzachiodi R, Byrne JH. (2010). More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory. Trends in neurosciences. 33 [PubMed]
Müller U, Carew TJ. (1998). Serotonin induces temporally and mechanistically distinct phases of persistent PKA activity in Aplysia sensory neurons. Neuron. 21 [PubMed]
Yiu AP et al. (2014). Neurons are recruited to a memory trace based on relative neuronal excitability immediately before training. Neuron. 83 [PubMed]
Zhang Y et al. (2011). Computational design of enhanced learning protocols. Nature neuroscience. 15 [PubMed]
Liu RY, Zhang Y, Smolen P, Cleary LJ, Byrne JH. (2022). Defective synaptic plasticity in a model of Coffin-Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways Learning & memory (Cold Spring Harbor, N.Y.). 29 [PubMed]
Liu RY, Zhang Y, Smolen P, Cleary LJ, Byrne JH. (2022). Defective synaptic plasticity in a model of Coffin-Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways Learning & memory (Cold Spring Harbor, N.Y.). 29 [PubMed]
Alberini CM, Ghirardi M, Metz R, Kandel ER. (1994). C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell. 76 [PubMed]
Bartsch D, Casadio A, Karl KA, Serodio P, Kandel ER. (1998). CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell. 95 [PubMed]
Bartsch D et al. (1995). Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell. 83 [PubMed]
Bourtchouladze R et al. (2003). A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4. Proceedings of the National Academy of Sciences of the United States of America. 100 [PubMed]
Chain DG et al. (1999). Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia. Neuron. 22 [PubMed]
Chin J, Angers A, Cleary LJ, Eskin A, Byrne JH. (1999). TGF-beta1 in Aplysia: role in long-term changes in the excitability of sensory neurons and distribution of TbetaR-II-like immunoreactivity. Learning & memory (Cold Spring Harbor, N.Y.). 6 [PubMed]
Choi YH et al. (2011). The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. The Journal of biological chemistry. 286 [PubMed]
Delaunoy JP, Dubos A, Marques Pereira P, Hanauer A. (2006). Identification of novel mutations in the RSK2 gene (RPS6KA3) in patients with Coffin-Lowry syndrome. Clinical genetics. 70 [PubMed]
Finkbeiner S et al. (1997). CREB: a major mediator of neuronal neurotrophin responses. Neuron. 19 [PubMed]
Guan Z et al. (2002). Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell. 111 [PubMed]
Jin I et al. (2018). Autocrine signaling by an Aplysia neurotrophin forms a presynaptic positive feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 115 [PubMed]
Liu RY, Cleary LJ, Byrne JH. (2011). The requirement for enhanced CREB1 expression in consolidation of long-term synaptic facilitation and long-term excitability in sensory neurons of Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]
Liu RY, Fioravante D, Shah S, Byrne JH. (2008). cAMP response element-binding protein 1 feedback loop is necessary for consolidation of long-term synaptic facilitation in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]
Liu RY, Neveu C, Smolen P, Cleary LJ, Byrne JH. (2017). Superior long-term synaptic memory induced by combining dual pharmacological activation of PKA and ERK with an enhanced training protocol. Learning & memory (Cold Spring Harbor, N.Y.). 24 [PubMed]
Liu RY et al. (2013). Deficit in long-term synaptic plasticity is rescued by a computationally predicted stimulus protocol. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]
Liu RY, Zhang Y, Smolen P, Cleary LJ, Byrne JH. (2020). Role of p90 ribosomal S6 kinase in long-term synaptic facilitation and enhanced neuronal excitability Scientific reports. 10 [PubMed]
Michael D et al. (1998). Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia. Proceedings of the National Academy of Sciences of the United States of America. 95 [PubMed]
Mohamed HA, Yao W, Fioravante D, Smolen PD, Byrne JH. (2005). cAMP-response elements in Aplysia creb1, creb2, and Ap-uch promoters: implications for feedback loops modulating long term memory. The Journal of biological chemistry. 280 [PubMed]
Montarolo PG et al. (1986). A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science (New York, N.Y.). 234 [PubMed]
Morice E et al. (2013). Defective synaptic transmission and structure in the dentate gyrus and selective fear memory impairment in the Rsk2 mutant mouse model of Coffin-Lowry syndrome. Neurobiology of disease. 58 [PubMed]
Mozzachiodi R, Byrne JH. (2010). More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory. Trends in neurosciences. 33 [PubMed]
Müller U, Carew TJ. (1998). Serotonin induces temporally and mechanistically distinct phases of persistent PKA activity in Aplysia sensory neurons. Neuron. 21 [PubMed]
Poirier R et al. (2007). Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior. Behavior genetics. 37 [PubMed]
Rawashdeh O, Jilg A, Maronde E, Fahrenkrug J, Stehle JH. (2016). Period1 gates the circadian modulation of memory-relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK. Journal of neurochemistry. 138 [PubMed]
Sapkota GP et al. (2007). BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. The Biochemical journal. 401 [PubMed]
Sharma SK, Carew TJ. (2004). The roles of MAPK cascades in synaptic plasticity and memory in Aplysia: facilitatory effects and inhibitory constraints. Learning & memory (Cold Spring Harbor, N.Y.). 11 [PubMed]
Sharma SK et al. (2003). Differential role of mitogen-activated protein kinase in three distinct phases of memory for sensitization in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]
Smolen P, Baxter DA, Byrne JH. (2014). Simulations suggest pharmacological methods for rescuing long-term potentiation. Journal of theoretical biology. 360 [PubMed]
Xing J, Ginty DD, Greenberg ME. (1996). Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science (New York, N.Y.). 273 [PubMed]
Xing J, Kornhauser JM, Xia Z, Thiele EA, Greenberg ME. (1998). Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Molecular and cellular biology. 18 [PubMed]
Zhang Y et al. (2011). Computational design of enhanced learning protocols. Nature neuroscience. 15 [PubMed]
Zhang Y, Smolen PD, Cleary LJ, Byrne JH. (2021). Quantitative description of the interactions among kinase cascades underlying long-term plasticity of Aplysia sensory neurons Scientific reports. 11 [PubMed]
Zhou L et al. (2015). Rescue of impaired long-term facilitation at sensorimotor synapses of Aplysia following siRNA knockdown of CREB1. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35 [PubMed]