Short term plasticity of synapses onto V1 layer 2/3 pyramidal neuron (Varela et al 1997)

This archive contains 3 mod files for NEURON that implement the short term synaptic plasticity model described in Varela, J.A., Sen, K., Gibson, J., Fost, J., Abbott, L.R., and Nelson, S.B.. A quantitative description of short-term plasticity at excitatory synapses in layer 2/3 of rat primary visual cortex. Journal of Neuroscience 17:7926-7940, 1997. Contact ted.carnevale@yale.edu if you have questions about this implementation of the model.

Model Type: Synapse

Region(s) or Organism(s): Visual cortex

Cell Type(s): Neocortex L2/3 pyramidal GLU cell

Currents: I Na,t; I K

Receptors: AMPA

Transmitters: Glutamate

Model Concept(s): Synaptic Plasticity; Short-term Synaptic Plasticity; Facilitation; Depression; Vision

Simulation Environment: NEURON

Implementer(s): Carnevale, Ted [Ted.Carnevale at Yale.edu]

References:

Varela JA et al. (1997). A quantitative description of short-term plasticity at excitatory synapses in layer 2/3 of rat primary visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]