Medial vestibular neuron models (Quadroni and Knopfel 1994)

The structure and the parameters of the model cells were chosen to reproduce the responses of type A and type B MVNns as described in electrophysiological recordings. The emergence of oscillatory firing under these two specific experimental conditions is consistent with electrophysiological recordings not used during construction of the model. We, therefore, suggest that these models have a high predictive value.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Vestibular neuron

Currents: I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I K; I h

Receptors: NMDA

Model Concept(s): Oscillations; Action Potentials; Calcium dynamics

Simulation Environment: NEURON

Implementer(s): Morse, Tom [Tom.Morse at]


Quadroni R, Knöpfel T. (1994). Compartmental models of type A and type B guinea pig medial vestibular neurons. Journal of neurophysiology. 72 [PubMed]

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