CA1 pyramidal neuron: signal propagation in oblique dendrites (Migliore et al 2005)


NEURON mod files from the paper: M. Migliore, M. Ferrante, GA Ascoli (2005). The model shows how the back- and forward propagation of action potentials in the oblique dendrites of CA1 neurons could be modulated by local properties such as morphology or active conductances.

Model Type: Dendrite

Cell Type(s): Hippocampus CA1 pyramidal GLU cell

Currents: I Na,t; I A; I K; I h

Receptors: AMPA

Transmitters: Glutamate

Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Ion Channel Kinetics; Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Action Potentials

Simulation Environment: NEURON; neuroConstruct (web link to model)

Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]

References:

Migliore M, Ferrante M, Ascoli GA. (2005). Signal propagation in oblique dendrites of CA1 pyramidal cells. Journal of neurophysiology. 94 [PubMed]


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