Simulation of experiments on olfactory receptor neurons (ORNs). Focussing on the negative feedback that calcium (through calmodulin) has on its own influx through CNG channels, this model is able to reproduce both calcium oscillations as well as adaptation behaviour as seen in experiments done with ORNs.
Model Type: Dendrite
Cell Type(s): Olfactory receptor GLU cell
Currents: I CNG
Simulation Environment: MATLAB
Borowski P. (2006). Stochastic dynamics in olfactory signal transduction and development, Dissertation http://nbn-resolving.de/urn:nbn:de:swb:14-1159519135136-2269.