Angulo SL et al. (2017). Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit. Neurobiology of disease. 108 [PubMed]

See more from authors: Angulo SL · Orman R · Neymotin SA · Liu L · Buitrago L · Cepeda-Prado E · Stefanov D · Lytton WW · Stewart M · Small SA · Duff KE · Moreno H

References and models cited by this paper

Cepeda-Prado E et al. (2012). R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

Chandler B, Grossberg S. (2012). Joining distributed pattern processing and homeostatic plasticity in recurrent on-center off-surround shunting networks: noise, saturation, short-term memory, synaptic scaling, and BDNF. Neural networks : the official journal of the International Neural Network Society. 25 [PubMed]

Crimins JL et al. (2011). Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy. Acta neuropathologica. 122 [PubMed]

DeVos SL et al. (2013). Antisense reduction of tau in adult mice protects against seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

Decker JM et al. (2016). The Tau/A152T mutation, a risk factor for frontotemporal-spectrum disorders, leads to NR2B receptor-mediated excitotoxicity. EMBO reports. 17 [PubMed]

Dickson CT, Biella G, de Curtis M. (2003). Slow periodic events and their transition to gamma oscillations in the entorhinal cortex of the isolated Guinea pig brain. Journal of neurophysiology. 90 [PubMed]

Fogel H et al. (2014). APP homodimers transduce an amyloid-ß-mediated increase in release probability at excitatory synapses. Cell reports. 7 [PubMed]

Gillespie AK et al. (2016). Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples. Neuron. 90 [PubMed]

Gloveli T, Schmitz D, Empson RM, Dugladze T, Heinemann U. (1997). Morphological and electrophysiological characterization of layer III cells of the medial entorhinal cortex of the rat. Neuroscience. 77 [PubMed]

Gnatkovsky V, Wendling F, de Curtis M. (2007). Cellular correlates of spontaneous periodic events in the medial entorhinal cortex of the in vitro isolated guinea pig brain. The European journal of neuroscience. 26 [PubMed]

Gómez-Isla T et al. (1996). Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Götz J, Ittner LM, Kins S. (2006). Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease? Journal of neurochemistry. 98 [PubMed]

Harris JA et al. (2010). Transsynaptic progression of amyloid-ß-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron. 68 [PubMed]

Hasselmo ME, Brandon MP. (2008). Linking cellular mechanisms to behavior: entorhinal persistent spiking and membrane potential oscillations may underlie path integration, grid cell firing, and episodic memory. Neural plasticity. 2008 [PubMed]

Holth JK et al. (2013). Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

Hsia AY et al. (1999). Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]

Hsieh H et al. (2006). AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron. 52 [PubMed]

Hunsberger HC, Rudy CC, Batten SR, Gerhardt GA, Reed MN. (2015). P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. Journal of neurochemistry. 132 [PubMed]

Hunsberger HC et al. (2015). Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression. Journal of neurochemistry. 135 [PubMed]

Ittner LM et al. (2010). Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell. 142 [PubMed]

Jackson RJ et al. (2016). Human tau increases amyloid ß plaque size but not amyloid ß-mediated synapse loss in a novel mouse model of Alzheimer's disease. The European journal of neuroscience. 44 [PubMed]

Jones RS, Heinemann U. (1989). Spontaneous activity mediated by NMDA receptors in immature rat entorhinal cortex in vitro. Neuroscience letters. 104 [PubMed]

Khan UA et al. (2014). Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease. Nature neuroscience. 17 [PubMed]

Kim S, Ziff EB. (2014). Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors. PLoS biology. 12 [PubMed]

Kim SM, Ganguli S, Frank LM. (2012). Spatial information outflow from the hippocampal circuit: distributed spatial coding and phase precession in the subiculum. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

Koppensteiner P et al. (2016). Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aß42: an early index of Alzheimer's disease. Scientific reports. 6 [PubMed]

Kunitake A, Kunitake T, Stewart M. (2004). Differential modulation by carbachol of four separate excitatory afferent systems to the rat subiculum in vitro. Hippocampus. 14 [PubMed]

Li S et al. (2009). Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron. 62 [PubMed]

Liu L et al. (2012). Trans-synaptic spread of tau pathology in vivo. PloS one. 7 [PubMed]

Lorenzo A et al. (2000). Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nature neuroscience. 3 [PubMed]

Lytton WW, Omurtag A, Neymotin SA, Hines ML. (2008). Just-in-time connectivity for large spiking networks. Neural computation. 20 [PubMed]

Lücke A, Nagao T, Köhling R, Avoli M. (1995). Synchronous potentials and elevations in [K+]o in the adult rat entorhinal cortex maintained in vitro. Neuroscience letters. 185 [PubMed]

Marcantoni A, Raymond EF, Carbone E, Marie H. (2014). Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model. Pflugers Archiv : European journal of physiology. 466 [PubMed]

Maurin H et al. (2014). Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy. PloS one. 9 [PubMed]

Menkes-Caspi N et al. (2015). Pathological tau disrupts ongoing network activity. Neuron. 85 [PubMed]

Miller EC et al. (2014). Tau phosphorylation and tau mislocalization mediate soluble Aß oligomer-induced AMPA glutamate receptor signaling deficits. The European journal of neuroscience. 39 [PubMed]

Minkeviciene R et al. (2009). Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Moreno H et al. (2011). Blocking Effects of Human Tau on Squid Giant Synapse Transmission and Its Prevention by T-817 MA. Frontiers in synaptic neuroscience. 3 [PubMed]

Moreno H et al. (2007). Imaging the Abeta-related neurotoxicity of Alzheimer disease. Archives of neurology. 64 [PubMed]

Moreno H et al. (2009). Synaptic transmission block by presynaptic injection of oligomeric amyloid beta. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

Nenov MN et al. (2014). Cognitive enhancing treatment with a PPAR? agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Neymotin SA et al. (2013). Ih tunes theta/gamma oscillations and cross-frequency coupling in an in silico CA3 model. PloS one. 8 [PubMed]

Neymotin SA et al. (2011). Ketamine disrupts ? modulation of ? in a computer model of hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Neymotin SA, Lee H, Park E, Fenton AA, Lytton WW. (2011). Emergence of physiological oscillation frequencies in a computer model of neocortex. Frontiers in computational neuroscience. 5 [PubMed]

Orman R, Von Gizycki H, Lytton WW, Stewart M. (2008). Local axon collaterals of area CA1 support spread of epileptiform discharges within CA1, but propagation is unidirectional. Hippocampus. 18 [PubMed]

Palop JJ et al. (2007). Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55 [PubMed]

Peng YR et al. (2009). Coordinated changes in dendritic arborization and synaptic strength during neural circuit development. Neuron. 61 [PubMed]

Pigino G et al. (2009). Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

Pooler AM et al. (2015). Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease. Acta neuropathologica communications. 3 [PubMed]

Pooler AM et al. (2013). Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology. The Journal of comparative neurology. 521 [PubMed]

Puzzo D et al. (2017). LTP and memory impairment caused by extracellular Aß and Tau oligomers is APP-dependent. eLife. 6 [PubMed]

Quilichini P, Sirota A, Buzsáki G. (2010). Intrinsic circuit organization and theta-gamma oscillation dynamics in the entorhinal cortex of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Ray S et al. (2014). Grid-layout and theta-modulation of layer 2 pyramidal neurons in medial entorhinal cortex. Science (New York, N.Y.). 343 [PubMed]

Roberson ED et al. (2011). Amyloid-ß/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Rowan MS, Neymotin SA, Lytton WW. (2014). Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease. Frontiers in computational neuroscience. 8 [PubMed]

Rutherford LC, Nelson SB, Turrigiano GG. (1998). BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. Neuron. 21 [PubMed]

Samura E et al. (2006). Enhanced accumulation of tau in doubly transgenic mice expressing mutant betaAPP and presenilin-1. Brain research. 1094 [PubMed]

Sanchez-Vives MV, McCormick DA. (2000). Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nature neuroscience. 3 [PubMed]

Santacruz K et al. (2005). Tau suppression in a neurodegenerative mouse model improves memory function. Science (New York, N.Y.). 309 [PubMed]

Sargolini F et al. (2006). Conjunctive representation of position, direction, and velocity in entorhinal cortex. Science (New York, N.Y.). 312 [PubMed]

Scala F et al. (2015). Intraneuronal Aß accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3. Neurobiology of aging. 36 [PubMed]

Seeburg DP, Feliu-Mojer M, Gaiottino J, Pak DT, Sheng M. (2008). Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity. Neuron. 58 [PubMed]

Shaked GM et al. (2006). Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624). FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20 [PubMed]

Sheng M, Sabatini BL, Südhof TC. (2012). Synapses and Alzheimer's disease. Cold Spring Harbor perspectives in biology. 4 [PubMed]

Sheroziya MG, von Bohlen Und Halbach O, Unsicker K, Egorov AV. (2009). Spontaneous bursting activity in the developing entorhinal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Squire LR, Alvarez P. (1995). Retrograde amnesia and memory consolidation: a neurobiological perspective. Current opinion in neurobiology. 5 [PubMed]

Stewart M. (1999). Columnar activity supports propagation of population bursts in slices of rat entorhinal cortex. Brain research. 830 [PubMed]

Stewart M, Wong RK. (1993). Intrinsic properties and evoked responses of guinea pig subicular neurons in vitro. Journal of neurophysiology. 70 [PubMed]

Tahvildari B, Alonso A. (2005). Morphological and electrophysiological properties of lateral entorhinal cortex layers II and III principal neurons. The Journal of comparative neurology. 491 [PubMed]

Tahvildari B, Fransén E, Alonso AA, Hasselmo ME. (2007). Switching between "On" and "Off" states of persistent activity in lateral entorhinal layer III neurons. Hippocampus. 17 [PubMed]

Tamagnini F, Scullion S, Brown JT, Randall AD. (2015). Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid ß peptide. Hippocampus. 25 [PubMed]

Traub RD, Whittington MA, Jefferys GR. (1999). Fast Oscillations In Cortical Circuits.

Turrigiano G. (2011). Too many cooks? Intrinsic and synaptic homeostatic mechanisms in cortical circuit refinement. Annual review of neuroscience. 34 [PubMed]

Turrigiano GG. (2008). The self-tuning neuron: synaptic scaling of excitatory synapses. Cell. 135 [PubMed]

Turrigiano GG, Leslie KR, Desai NS, Rutherford LC, Nelson SB. (1998). Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature. 391 [PubMed]

Unichenko P, Yang JW, Luhmann HJ, Kirischuk S. (2015). Glutamatergic system controls synchronization of spontaneous neuronal activity in the murine neonatal entorhinal cortex. Pflugers Archiv : European journal of physiology. 467 [PubMed]

Verret L et al. (2012). Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell. 149 [PubMed]

Walther H, Lambert JD, Jones RS, Heinemann U, Hamon B. (1986). Epileptiform activity in combined slices of the hippocampus, subiculum and entorhinal cortex during perfusion with low magnesium medium. Neuroscience letters. 69 [PubMed]

Ward AM et al. (2015). Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits. Neurobiology of aging. 36 [PubMed]

Whitwell JL et al. (2007). 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain : a journal of neurology. 130 [PubMed]

Witter MP. (2010). Connectivity of the hippocampus Hippocampal Microcircuits.

Witter MP, Moser EI. (2006). Spatial representation and the architecture of the entorhinal cortex. Trends in neurosciences. 29 [PubMed]

Wong RK, Bianchi R, Chuang SC, Merlin LR. (2005). Group I mGluR-induced epileptogenesis: distinct and overlapping roles of mGluR1 and mGluR5 and implications for antiepileptic drug design. Epilepsy currents. 5 [PubMed]

Wozny C et al. (2005). Entorhinal cortex entrains epileptiform activity in CA1 in pilocarpine-treated rats. Neurobiology of disease. 19 [PubMed]

Zempel H, Mandelkow EM. (2012). Linking amyloid-ß and tau: amyloid-ß induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton. Neuro-degenerative diseases. 10 [PubMed]

de Calignon A et al. (2012). Propagation of tau pathology in a model of early Alzheimer's disease. Neuron. 73 [PubMed]

van Rossum MC, Bi GQ, Turrigiano GG. (2000). Stable Hebbian learning from spike timing-dependent plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

van Strien NM, Cappaert NL, Witter MP. (2009). The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network. Nature reviews. Neuroscience. 10 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.