Huang CW, Tsai JJ, Huang CC, Wu SN. (2009). Experimental and simulation studies on the mechanisms of levetiracetam-mediated inhibition of delayed-rectifier potassium current (KV3.1): contribution to the firing of action potentials. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 60 [PubMed]

See more from authors: Huang CW · Tsai JJ · Huang CC · Wu SN

References and models cited by this paper

Baranauskas G. (2007). Ionic channel function in action potential generation: current perspective. Molecular neurobiology. 35 [PubMed]

Beran RG et al. (2005). Efficacy and safety of levetiracetam 1000-3000 mg/day in patients with refractory partial-onset seizures: a multicenter, open-label single-arm study. Epilepsy research. 63 [PubMed]

Brette R et al. (2007). Simulation of networks of spiking neurons: a review of tools and strategies. Journal of computational neuroscience. 23 [PubMed]

Bukanova JV, Solntseva EI, Skrebitsky VG. (2002). Selective suppression of the slow-inactivating potassium currents by nootropics in molluscan neurons. The international journal of neuropsychopharmacology. 5 [PubMed]

Carreno M. (2007). Levetiracetam. Drugs of today (Barcelona, Spain : 1998). 43 [PubMed]

Cereghino JJ et al. (2000). Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology. 55 [PubMed]

Coetzee WA et al. (1999). Molecular diversity of K+ channels. Annals of the New York Academy of Sciences. 868 [PubMed]

Crowder KM et al. (1999). Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]

Destexhe A, Rudolph M, Paré D. (2003). The high-conductance state of neocortical neurons in vivo. Nature reviews. Neuroscience. 4 [PubMed]

Erisir A, Lau D, Rudy B, Leonard CS. (1999). Function of specific K(+) channels in sustained high-frequency firing of fast-spiking neocortical interneurons. Journal of neurophysiology. 82 [PubMed]

Ermentrout GB. (2002). Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students Society for Industrial and Applied Mathematics (SIAM).

Futatsugi Y, Riviello JJ. (1998). Mechanisms of generalized absence epilepsy. Brain & development. 20 [PubMed]

Genton P, Van Vleymen B. (2000). Piracetam and levetiracetam: close structural similarities but different pharmacological and clinical profiles. Epileptic disorders : international epilepsy journal with videotape. 2 [PubMed]

Gillard M, Chatelain P, Fuks B. (2006). Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein. European journal of pharmacology. 536 [PubMed]

Gorji A et al. (2002). Effect of levetiracetam on epileptiform discharges in human neocortical slices. Epilepsia. 43 [PubMed]

Ho CS, Grange RW, Joho RH. (1997). Pleiotropic effects of a disrupted K+ channel gene: reduced body weight, impaired motor skill and muscle contraction, but no seizures. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]

Huang CW, Huang CC, Lin MW, Tsai JJ, Wu SN. (2008). The synergistic inhibitory actions of oxcarbazepine on voltage-gated sodium and potassium currents in differentiated NG108-15 neuronal cells and model neurons. The international journal of neuropsychopharmacology. 11 [PubMed]

Huang CW, Huang CC, Wu SN. (2007). Activation by zonisamide, a newer antiepileptic drug, of large-conductance calcium-activated potassium channel in differentiated hippocampal neuron-derived H19-7 cells. The Journal of pharmacology and experimental therapeutics. 321 [PubMed]

Joho RH, Ho CS, Marks GA. (1999). Increased gamma- and decreased delta-oscillations in a mouse deficient for a potassium channel expressed in fast-spiking interneurons. Journal of neurophysiology. 82 [PubMed]

Kaminski RM et al. (2008). SV2A protein is a broad-spectrum anticonvulsant target: functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy. Neuropharmacology. 54 [PubMed]

Kawaguchi A et al. (2007). Enhancement of sodium current in NG108-15 cells during neural differentiation is mainly due to an increase in NaV1.7 expression. Neurochemical research. 32 [PubMed]

Kossoff EH, Bergey GK, Freeman JM, Vining EP. (2001). Levetiracetam psychosis in children with epilepsy. Epilepsia. 42 [PubMed]

Lo YK, Chiang HT, Wu SN. (2003). Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. Biochemical pharmacology. 65 [PubMed]

Lukyanetz EA, Shkryl VM, Kostyuk PG. (2002). Selective blockade of N-type calcium channels by levetiracetam. Epilepsia. 43 [PubMed]

Lynch BA et al. (2004). The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proceedings of the National Academy of Sciences of the United States of America. 101 [PubMed]

Madeja M et al. (2003). Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action? Neuropharmacology. 45 [PubMed]

Marom S. (1998). Slow changes in the availability of voltage-gated ion channels: effects on the dynamics of excitable membranes. The Journal of membrane biology. 161 [PubMed]

Martina M, Schultz JH, Ehmke H, Monyer H, Jonas P. (1998). Functional and molecular differences between voltage-gated K+ channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Martina M, Yao GL, Bean BP. (2003). Properties and functional role of voltage-dependent potassium channels in dendrites of rat cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Meador KJ et al. (2007). Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam. Neurology. 69 [PubMed]

Mercik K, Mozrzymas JW, Teisseyre A. (2007). The modulatory effect of zinc ions on voltage-gated potassium currents in cultured rat hippocampal neurons is not related to Kv1.3 channels. J Physiol Pharmacol. 58

Mohan DK, Molnar P, Hickman JJ. (2006). Toxin detection based on action potential shape analysis using a realistic mathematical model of differentiated NG108-15 cells. Biosensors & bioelectronics. 21 [PubMed]

Monti B et al. (2007). Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death. Journal of neurochemistry. 103 [PubMed]

Noachtar S et al. (2008). Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures. Neurology. 70 [PubMed]

Porcello DM, Ho CS, Joho RH, Huguenard JR. (2002). Resilient RTN fast spiking in Kv3.1 null mice suggests redundancy in the action potential repolarization mechanism. Journal of neurophysiology. 87 [PubMed]

Rehni AK, Singh N, Jindal S. (2007). Role of ATP-sensitive potassium channels in the piracetam induced blockade of opioid effects. Indian journal of experimental biology. 45 [PubMed]

Ridley JM, Shuba YM, James AF, Hancox JC. (2008). Modulation by testosterone of an endogenous hERG potassium channel current. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 59 [PubMed]

Rogawski MA. (2006). Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy research. 69 [PubMed]

Rudy B, McBain CJ. (2001). Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing. Trends in neurosciences. 24 [PubMed]

Sacco T, De Luca A, Tempia F. (2006). Properties and expression of Kv3 channels in cerebellar Purkinje cells. Molecular and cellular neurosciences. 33 [PubMed]

Solntseva EI et al. (1997). The effects of piracetam and its novel peptide analogue GVS-111 on neuronal voltage-gated calcium and potassium channels. General pharmacology. 29 [PubMed]

Song WJ. (2002). Genes responsible for native depolarization-activated K+ currents in neurons. Neuroscience research. 42 [PubMed]

Teisseyre A, Duarte N, Ferreira MJ, Michalak K. (2009). Influence of the multidrug transporter inhibitors on the activity of Kv1.3 voltage-gated potassium channels. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 60 [PubMed]

Tsai TY, Tsai YC, Wu SN, Liu YC. (2006). Tramadol-induced blockade of delayed rectifier potassium current in NG108-15 neuronal cells. European journal of pain (London, England). 10 [PubMed]

Wang YJ, Lin MW, Lin AA, Peng H, Wu SN. (2008). Evidence for state-dependent block of DPI 201-106, a synthetic inhibitor of Na+ channel inactivation, on delayed-rectifier K+ current in pituitary tumor (GH3) cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 59 [PubMed]

Wu SN, Chiang HT, Jan CR, Liu CP. (2003). Mechanism of carvedilol-induced block of delayed rectifier K+ current in the NG108-15 neuronal cell line Drug Develop Res. 58

Wu SN, Jan CR, Li HF, Chiang HT. (2000). Characterization of inhibition by risperidone of the inwardly rectifying K(+) current in pituitary GH(3) cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 23 [PubMed]

Wu SN, Lo YK, Chen H, Li HF, Chiang HT. (2001). Rutaecarpine-induced block of delayed rectifier K+ current in NG108-15 neuronal cells. Neuropharmacology. 41 [PubMed]

Xu M, Cao R, Xiao R, Zhu MX, Gu C. (2007). The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Yang XF, Weisenfeld A, Rothman SM. (2007). Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission. Epilepsia. 48 [PubMed]

Yeung SY, Thompson D, Wang Z, Fedida D, Robertson B. (2005). Modulation of Kv3 subfamily potassium currents by the sea anemone toxin BDS: significance for CNS and biophysical studies. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Yokoyama S et al. (1993). Potassium channels cloned from NG108-15 neuroblastoma-glioma hybrid cells. Functional expression in Xenopus oocytes and mammalian fibroblast cells. Annals of the New York Academy of Sciences. 707 [PubMed]

von Rosenstiel P. (2007). Brivaracetam (UCB 34714). Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 4 [PubMed]

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