In this study, four models of IP3R (Othmer and Tang, 1993; Dawson et al., 2003; Fraiman and Dawson, 2004; Doi et al., 2005) were selected among many to examine their behavior and compare them with experimental data available in literature. The provided MATLAB script (run_IP3R_P0.m) will run the simulations and plot Figure 2A in the paper.
Model Type: Channel/Receptor
Region(s) or Organism(s): Unknown
Receptors: IP3
Model Concept(s): Ion Channel Kinetics; Calcium waves
Simulation Environment: STEPS
Implementer(s): Hituri, Katri [katri.hituri at gmail.com]
References:
Hituri K, Linne ML. (2013). Comparison of models for IP3 receptor kinetics using stochastic simulations. PloS one 8 [PubMed]