" … Here we present a model for working memory which relies on the modulation of the intrinsic excitability properties of neurons, instead of synaptic plasticity, to retain novel information for periods of seconds to minutes. We show that it is possible to effectively use this mechanism to store the serial order in a sequence of patterns of activity. … The presented model exhibits properties which are in close agreement with experimental results in working memory. ... "
Model Type: Realistic Network
Model Concept(s): Working memory
Simulation Environment: NEURON
References:
Conde-Sousa E, Aguiar P. (2013). A working memory model for serial order that stores information in the intrinsic excitability properties of neurons. Journal of computational neuroscience. 35 [PubMed]