Recent evidence suggests that short-term dynamics of excitatory synaptic transmission is correlated to stereotypical connectivity motifs. We show that these connectivity motifs emerge in networks of model neurons, from the interactions between short-term synaptic dynamics (SD) and long-term spike-timing dependent plasticity (STDP).
Model Type: Realistic Network; Synapse; Neural mass
Region(s) or Organism(s): Neocortex; Olfactory bulb; Prefrontal cortex (PFC)
Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Olfactory bulb main mitral GLU cell
Transmitters: Glutamate
Model Concept(s): Simplified Models; Connectivity matrix; Olfaction
Simulation Environment: C or C++ program; MATLAB
Implementer(s): Giugliano, Michele [mgiugliano at gmail.com]
References:
Vasilaki E, Giugliano M. (2014). Emergence of connectivity motifs in networks of model neurons with short- and long-term plastic synapses. PloS one 9 [PubMed]