This research developed a neural network simulation constrained by known neuroanatomy and neurophysiology to generate ideas about the etiology of Borderline Personality Disorder. The simulations suggest an important role for the amygdala-ventromedial prefrontal cortex-amygdala circuit.
Region(s) or Organism(s): Amygdala; Prefrontal cortex (PFC); Brainstem
Model Concept(s): Long-term Synaptic Plasticity; Borderline Personality Disorder (BPD)
Simulation Environment: C or C++ program
Implementer(s): Berdahl, Carl H [Carl.Berdahl at verizon.net]
References:
Berdahl CH. (2010). A neural network model of Borderline Personality Disorder. Neural networks : the official journal of the International Neural Network Society 23 [PubMed]