MCCAIS model (multicompartmental cooperative AIS) (Öz et al 2015)

Action potential initiation in a multi-compartmental model with cooperatively gating Na channels in the axon initial segment.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Neocortex L5/6 pyramidal GLU cell

Currents: I Na,t; I K; I K,leak

Model Concept(s): Detailed Neuronal Models; Action Potential Initiation; Action Potentials; Axonal Action Potentials

Simulation Environment: C or C++ program

Implementer(s): Oz, Pinar [poz.neuro AT gmail.com]; Kreissl, Michael [mig80 AT gmx.net]

References:

Öz P, Huang M, Wolf F. (2015). Action potential initiation in a multi-compartmental model with cooperatively gating Na channels in the axon initial segment. Journal of computational neuroscience. 39 [PubMed]